Clinical improvement in patients with borderline personality disorder after treatment with repetitive transcranial magnetic stimulation: preliminary results.
نویسندگان
چکیده
OBJECTIVE Current treatment of borderline personality disorder (BPD) consists of psychotherapy and pharmacological interventions. However, the use of repetitive transcranial magnetic stimulation (rTMS) could be beneficial to improve some BPD symptoms. The objective of this study was to evaluate clinical improvement in patients with BPD after application of rTMS over the right or left dorsolateral prefrontal cortex (DLPFC). METHOD Twenty-nine patients with BPD from the National Institute of Psychiatry, Mexico, were randomized in two groups to receive 15 sessions of rTMS applied over the right (1 Hz, n=15) or left (5 Hz, n=14) DLPFC. Improvement was measured by the Clinical Global Impression Scale for BPD (CGI-BPD), Borderline Evaluation of Severity Over Time (BEST), Beck Depression Inventory (BDI), Hamilton Anxiety Rating Scale (HAM-A), and Barratt Impulsiveness Scale (BIS). RESULTS Intragroup comparison showed significant (p < 0.05) reductions in every psychopathologic domain of the CGI-BPD and in the total scores of all scales in both groups. CONCLUSIONS Both protocols produced global improvement in severity and symptoms of BPD, particularly in impulsiveness, affective instability, and anger. Further studies are warranted to explore the therapeutic effect of rTMS in BPD. CLINICAL TRIAL REGISTRATION NCT02273674
منابع مشابه
اثربخشی تحریک مکرر مغناطیسی مغز بر حافظه کاری بیماران مبتلا به اختلال افسردگی اساسی مقاوم به درمان
Background: Major depression disorder is one of the most common psychiatric disorders which is associated with impairment in cognitive functions, including working memory. In recent decades, a non-invasive and painless technique, called Repetitive Transcranial Magnetic Stimulation (rTMS) has been used in treatment of treatment-resistant depressions. Current study was conducted to investigate th...
متن کاملThe effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) on the treatment of aphasia caused by cerebrovascular accident (CVA)
Background: Aphasia is a common outcome of Cerebrovascular Accident (CVA) in which clinical interventions have limited effectiveness. Some evidence suggests that noninvasive stimulation of the brain can have beneficial effects in the treatment of CVA induced aphasia. In patients with motor aphasia, repetitive Transcranial Magnetic Stimulation (rTMS) is used to facilitate long-term improvement i...
متن کاملThe Effect of Repetitive Transcranial Magnetic Stimulation on Postural Stability After Acute Stroke: A Clinical Trial
Introduction: Balance impairment is a common problem and a major cause of motor disability after stroke. Therefore, this study aimed to investigate whether low-frequency repetitive Transcranial Magnetic Stimulation (rTMS) improves the postural balance problems in stroke patients. Methods: This randomized double blind clinical trial with 12 weeks follow-up was conducted on stroke patients. Trea...
متن کاملSafety and Therapeutic Effects of Repetitive Transcranial Magnetic Stimulation and Behavior Therapy in a Pregnant Woman: Case Report
In this study, the authors reported a case of woman with severe compulsion who became pregnant during the Repetitive transcranial magnetic stimulation. We carried out Repetitive transcranial magnetic stimulation and behavior therapy simultaneously after repeated medications' refraction. The patient received 20 sessions 1 Hz Repetitive transcranial magnetic stimulation in right dorsolateral pref...
متن کاملSlow-frequency rTMS reduces fibromyalgia pain.
OBJECTIVE Evidence suggests that fibromyalgia (FM) is a centrally mediated pain disorder. Antidepressants, including electroconvulsive therapy, provide some symptomatic relief in FM and other pain disorders. Repetitive transcranial magnetic stimulation (rTMS) is a new antidepressant treatment, which may also be useful in treating chronic pain. DESIGN As part of a larger study, four women with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Revista brasileira de psiquiatria
دوره 40 1 شماره
صفحات -
تاریخ انتشار 2018